Brian Litt, MD is an expert in collaborative, multidisciplinary  research bridging engineering, neuroscience, and clinical medicine. His  lab focuses on applying new engineering technology to map and modulate  functional networks in brain to understand and treat human disease. As  PI and co-Investigator on government, institutional, and privately  funded grants, he engages and innovates in the areas of hardware design, machine learning, cloud-based informatics/ signal processing and  brain-computer interfaces. Clinical translation is an important goal of  his work, in addition to mentoring clinicians and scientists across  fields. Dr. Litt’s work is both individual and collaborative and often  involves multiple institutions and fields.

In recent years, as  Director of Penn Health-Tech, he has coordinated selecting, funding, and mentoring over 60 projects out of Penn, many in the neuroengineering  space, and set up an infrastructure to manage this for Penn and  ultimately to spread it through Philadelphia and the surrounding region, in collaboration with multiple universities, the Philadelphia Science  Center and the CHOP FDA-funded Philadelphia Pediatric Device Consortium.

He has also promoted these types of activities worldwide through neurology and engineering collaborations with universities,  corporations and government run initiatives. Personally, he is  co-inventor, founder, and participant in several successful neurodevice  companies including NeuroPace, MC10, Hyperfine, Liminal, Blackfynn,  identifeye HEALTH, Butterfly IQ, and consulted and collaborated with  device companies including NeuroPace, Boston Scientific, Medtronic, and  others. His collaborative group is composed of clinical and basic  scientists and engineers; their activities are enhanced by the Penn  Center for Neuroengineering and Therapeutics which he directs. His lab  emphasizes training in research and is committed to training  pre-doctoral and post-doctoral trainees and junior faculty to become  clinical and translational scientists. In addition to clinical trainees, Dr. Litt has successfully mentored over 80 doctoral candidates and  post-doctoral researchers, including 9 NIH K08/K23/K12K-awardees, and 3  K99-R00 awardees.